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Effektivität und Effizienz von psychologischen, psychiatrischen, sozialmedizinischen und komplementärmedizinischen Therapien bei Schreibabys

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Erste Therapieansätze bei Progerie: Lonafarnib

The children came from all over the world: 28 families from 16 countries, speaking over a dozen languages. They faced a grim prognosis: death at an average age of 13 from cardiovascular disease. Not the congenital heart defects we so commonly see in babies coming to Boston Children’s Hospital, but the kind of disease you might find in an 80-year-old: atherosclerosis, heart attacks, strokes.

Trial participant Megan Nighbor (now age 12) in 2008 (courtesy Progeria Research Foundation)The children represented three-quarters of the then-known world population with Hutchinson-Gilford Progeria Syndrome, or progeria—a rare, fatal genetic condition in which children seem to age prematurely. When they began arriving at the Clinical Translational Study Unit at Boston Children’s in 2007, most had already lost body fat and hair, had the thin, tight skin typical of elderly people, and were suffering from hearing loss, osteoporosis, hardening of the arteries, stiff joints and failure to grow.

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New Research in Tissue Engineering of cardiomyocytes in children With Heart failure

Summary of Scott Howe`s article "A regenerative approach to heart failure in children?" out of "Vector" Boston Children`s Hospital science and clinical innovation blog.

Research done by Bernhard Kühn, MD, at Boston Children`s Hospital and colleagues support the idea that young people, including infants, not yet past adolescence can create new cardiomyocytes.

New recent research using zebrafish and newborn mice brings up the possibility that some young animals are capable of generating new heart muscle by divisding muscle cells.This correlates with research results in the 1930s and 1940s which suggested that the division of cardiomyocytes might still take place AFTER birth.

According to Kühn, it is difficult to study heart cell growth directly, because healthy hearts cannot be easily found for this purpose.

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Dank an Gutachter

» Acknowledgement to Reviewers: Forsch Komplementmed 2012; 19:284 (pdf)

 
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Leiter des Ped Mind Institutes
Stefan Bittmann, M.D., M.A.
Weissenstein A, Villalon G, Luchter E, Bittmann S:
“Pipeline bandage with marigold essence in pediatric bee sting lesions”
Applied Medical Research 1 (1):32-34, 2015
» publication download

Weissenstein A, Villalon G, Luchter E, Bittmann S:
Tumor suppressor candidate 3 gene (TUSC 3) deletion correlates with mental retardation in a child”
Applied Medical Research 1 (1): 35-36, 2015
» publication download

Weissenstein A, Villalon G, Luchter E, Bittmann S:
“A newborn with a missing cerebrum”
Applied Medical Research (1):37-38, 2015
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Weissenstein A, Luchter E, Bittmann S
"Successful treatment of infantile haemangioma with propranolol"
accepted for publication, British Journal of Nursing 02/2015
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Weissenstein A, Luchter E, Bittmann S:
"Alice in Wonderland Syndrome: a rare neurological manifestation with microscopy in a 6 years old child"
accepted for publication in: Journal of Pediatric Neurosciences 12/2014
» publication download

Weissenstein A, Villalon G, Luchter E, Bittmann:
"Vaccine patches in pediatrics: future or false hope?"
International Journal of Innovative Medicine and Health Sciences (UK), Vol.2, 6-10, 2014
» publication download